Summit, NJ, United States
Nov 19, 2020
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
Cell Therapy is one of the most groundbreaking new forms of cancer treatments being studied today. With therapies only in their infancy and BMS’s continued investment in our Cell Therapy capabilities, the growth potential of this science, your career, and the ability to help patients are incredible.
The primary focus of the Associate Director/Director, External Manufacturing role is to build and lead ‘virtual plant teams’ (VPTs), that interface closely with the BMS external manufacturing network as well as internal stakeholders, to ensure flawless execution of the BMS vision. We are looking for a leader with the breadth of professional experience and the drive to work with both internal and Contract Manufacturing Organizations (CMOs) to define and implement our plans. The candidate will be responsible for ensuring the right network partners are identified in a timely manner and are subsequently managed appropriately to assure robust supply of Celgene cell therapy products. The right candidate should have proven experience in implementation of strategic initiative in dynamic business environment, a solid technical operational background, and understand the challenges and impact of identifying, selecting, and managing CMO partners. The candidate should be able to adapt to risks/changes associated with the highly novel technologies and distill trade-off decisions into recommendations for escalation to leadership/negotiation with CMOs, to meet the BMS program objectives. The successful candidate will be ultimately responsible for successful execution of the vector manufacturing strategy at the CMO site(s).
As we are “changing medicine for good,” we are looking for leaders who can work in a highly matrixed and cross-functional organizations, against tight deadlines, and with world-class contract manufacturers and business leaders alike.
Lead high-functioning VPTs where cross-functional team members are accountable, as both functional as well as program representatives, for prioritization and execution the BMS strategy
Drive delivery of the vector program against aggressive timelines by anticipating and managing risks and proactively developing mitigation plans
Develop and maintain strong strategic relationships within the CMO organization to ensure the best outcome for BMS assets
Partner with key stakeholders to establish a vendor management/governance program to track and report compliance with commitment in existing agreements (including but not limited to SoWs, commercial and clinical supply agreements and quality agreements)
Identify and escalate business-critical issues effecting CMO operation/management to BMS senior management with recommendations around potential solutions
Partner with CMOs and internal stakeholders to draft, manage, and deliver on annual CMO performance targets, and operating budget.
Manage and coordinate post-approval lifecycle strategy implementation, including a robust business continuity program for the CMOs.
Ensure alignment of objectives and priorities with CMC Strategy Team, representing the VPT and CMOs in strategic decisions for the program.
Collaborate with CMO and internal stakeholders to understand planned change and manage the E-2-E implementation process
Act as the primary liaison with the CMOs to manage BMS expectations by disciplined tracking of scope and delivery against objectives/metrics including but not limited to quality, regulatory, safety and environmental compliance, robust and timely supply, change management and budget/spend management
Engage with BMS development teams to understand requirements of BMS asset/technology pipeline and collaborate with cross functional stakeholders in the development of a world class CMO network to support the commercialization of the same
Provide business insight for negotiation and execution of contractual documents with CMOs – focus on creating risk-sharing frameworks to support the fluidity associated with novel technologies
Live the BMS values
Bachelor’s degree required, with a strong technical background in cell biology, immunology, or closely related discipline - Advanced Degree preferred
10 years of experience working in biopharmaceutical manufacturing, supply chain, or pharmaceutical development
Demonstrated ability to lead matrix teams; strong experience supporting best practices.
Demonstrated experience in management of CMOs
Strong quantitative and qualitative analytical abilities
Ability to influence senior management both internally and externally
Strong leadership and an innate ability to collaborate and build relationships is critical
Ability to expresses one’s self clearly and concisely, by adjusting style, language and/or terminology as appropriate for the audience
Strong background in technical operations – experience in aseptic operations preferred
Experience in commercialization of new assets, through launch, and management of post-approval changes
Flexible and comfortable working with ambiguity as the program priorities follow the science and clinical outcomes
Zeal for innovation and problem-solving
Bachelor’s degree in Life Sciences or related discipline (Immunology, Microbiology, Cell Biology, Engineering, etc.).
Advanced degree in Life Sciences and/or MBA preferred
If you want to challenge yourself, accelerate your career, and give new hope to patients, there’s no better place than here with our Cell Therapy team. Full of incredible and dedicated team members, those working on CAR-T and other forms of Cell Therapy are transforming patients’ lives through science. From studying individualized cell lines to making brand new discoveries, this bold and personal discipline allows you to grow your career while making a lasting impact on the field of medicine. Join us today.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Company: Bristol Myers Squibb
Req Number: R1533240-en-us
Updated: 2020-11-21 10:40:37.223 UTC
Location: Summit,New Jersey
Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.